The 2020–21 Scottish League One was the eighth season of Scottish League One, the third tier of Scottish football. The season commenced later than usual, on the October 17th, being played over a shortened 22 game period due to the ongoing coronavirus pandemic.

Ten teams contested the league: Airdrieonians, Clyde, Cove Rangers, Dumbarton, East Fife, Falkirk, Forfar Athletic, Montrose, Partick Thistle and Peterhead.

On 11 January 2021, the league was suspended for three weeks due to the COVID-19 pandemic. On 29 January 2021, the suspension was extended until at least 14 February. In March 2021, the Scottish Government gave permission for the league to resume. On 4 March, League One and Two clubs proposed shortening the season to 22 matches, with each team playing all other teams twice, followed by a split in the table to determine the final four matches. The clubs suggested a restart date of 20 March, which was approved by the SPFL.